9,10-BIS[(4-(2-HYDROXYETHYL)PIPERAZINE-1-YL)PROP-2-YNE-1-YL]ANTHRACENE: SYNTHESIS AND G-QUADRUPLEX SELECTIVITY

9,10-Bis[(4-(2-hydroxyethyl)piperazine-1-yl)prop-2-yne-1-yl]anthracene: Synthesis and G-quadruplex Selectivity

G-quadruplex DNA is the target of several natural and synthetic small molecules with antiproliferative and antiviral activity.We here Idler Pulleys report the synthesis through Sonogashira reaction and A3 coupling of a disubstituted anthracene derivative, 9,10-bis[(4-(2-hydroxyethyl)piperazine-1-yl)prop-2-yne-1-yl]anthracene.The binding of this com

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Anamorphic and Local Characterization of a Holographic Data Storage System with a Liquid-Crystal on Silicon Microdisplay as Data Pager

In this paper, we present a method to characterize a complete optical Holographic Data Storage System (HDSS), where we identify the elements that limit the # Veterinary supplies : First aid capacity to register and restore the information introduced by means of a Liquid Cristal on Silicon (LCoS) microdisplay as the data pager.In the literature, it

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Megaesophagus

Achalasia is a disorder of the primary motility of the esophagus characterized by insufficient relaxation of the lower part esophageal sphincter and absence of esophageal peristalsis, clinically it presents dysphagia for solids and liquids and "bird-beak" appearance on endoscopic and radiological studies.A 77-year-old man presented at our emergency

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